Turner syndrome dating
Ultrasound and maternal serum screening are not diagnostic, and to make a prenatal diagnosis of TS, karyotype confirmation is obligatory.
However, there are very few TS studies that would qualify as guidance for evidence-based recommendations, and hence most of the following guidelines represent the experts’ consensus judgments given the best information available.
Increased nuchal translucency on ultrasound is frequently seen in TS but may also be observed in autosomal trisomy syndromes.
The presence of cystic hygromas make the diagnosis of TS more likely (8).
We suggest a comprehensive educational evaluation in early childhood to identify potential attention-deficit or nonverbal learning disorders.
We suggest that caregivers address the prospect of premature ovarian failure in an open and sensitive manner and emphasize the critical importance of estrogen treatment for feminization and for bone health during the adult years.